La Folie, Quo Vadis, Evo-Devo?

1989
Li, K. C. and Duan, N. (1989). Regression analysis under link violation. Ann. Statist. 17, 1009-1052.
　
Li, K. C. and Ylvisaker, D. (1989). Another look at adaptation on the average. Statistics and Probability Letters 7, 381-383.
　

http://www.nature.com/nrg/journal/v10/n1/full/nrg2510.html
Thermodynamic models of gene expression:
Assumption ~ the level of gene expression is proportional to the equilibrium probability that RNA polymerase is bound to the promoter of interest

Rosetta Inpharmatics, LLC / Merck & Company, Inc.
簡單說起來就是跨越學術與業界的大頭, 27 March 2008時在nature一次發了兩篇articles (謎:真是發)
Genetics of gene expression and its effect on disease
Variations in DNA elucidate molecular networks that cause disease

Theodosius Dobzhansky:
"Nothing in biology makes sense except in the light of evolution"
另外想知道哪些人最近幹了哪些事:

這是我在碩士班時學的~~這要感謝老許的指導 <(_ _)>
一樣依照我個人風格, 本篇文章一率採用cluster寫作法, 並且dynamic update....
話說看看paper有三種層次, 前兩種我會簡略說過, 因為大部分人是採用前兩種, 第三種是我目前的看法但內容會因人而異並且個人風格很重:
第一種: keyword search, 這雖然是基本功夫, 但身為一個科學研究者, 不應該呆在這太久; 如字面意思, 這是寫報告挑seminar的好伴侶.

達爾文在天國一定會保佑我的, 雖然我知道他一定是被打入地獄, 但這兩篇可以讓他上天堂(完全不知道這三句怎麼來的...XD)
先介紹人物:
E. V. Koonin: NCBI裡面的COGs就是他搞的, 他有多大頭呢? NCBI的FTP有他個人的資料夾(ftp://ftp.ncbi.nih.gov/pub), 還有他自己創一個Biology Direct(http://www.biology-direct.com/), 這Biology Direct有多嗆呢? 月刊, 一期大約十篇以內, 標題都是很聳動的, 比如說"Evolution of complexity in RNA-like replicator systems"(這標題應該只有他敢收吧)
Y. I. Wolf: 除了創立自己的期刊, 其他同上
L. Carmel: Koonin的visting fellow

http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2958.2008.06221.x
Molecular Microbiology, doi:10.1111/j.1365-2958.2008.06221.x
Michael A. Savageau的大作~~~就是這傢伙狂推MCA......
這篇主用MCA來模擬E. coli signal transduction(Two component systems(TCS))其中的EnvZ/OmpR system
從abstrat得知(偶抓不到), 他是利用對E. coli這套訊號傳遞系統的模擬, 來探討TCS network bistability的存在性

The evolution of molecular biology into systems biology
ature Biotechnology 22, 1249 - 1252 (2004)
Published online: 6 October 2004; | doi:10.1038/nbt1020
http://www.nature.com/nbt/journal/v22/n10/full/nbt1020.html

http://www.sciencemag.org/content/vol319/issue5871/index.dtl
自從DNA被那兩位最年輕的諾貝爾獎得主搞大以後
RNA瞬間變成冷門研究直到最近幾年鹹魚大翻身
這期的SCIENCE就出了一篇專欄為RNA平反.....其實沒那麼糟

HCL - Hierarchical clustering
Eisen, M.B., P.T. Spellman, P.O. Brown, and D. Botstein. 1998. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. USA 95:14863-14868.
ST - Support trees (Bootstrapping)
Graur, D., and W.-H. Li. 2000. Fundamentals of Molecular Evolution. Second Edition.Sinauer Associates, Sunderland, MA. pp 209-210.